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Whitening miracle ingredient ---- glabridin

Views: 0     Author: Site Editor     Publish Time: 2022-12-09      Origin: Site

In so many kinds of cosmetic ingredients, the price of glabridin is quite expensive, known as "whitening gold".

Let's learn about such an expensive whitening ingredients, its whitening mechanism of action and whitening effect.


First of all, we would like to briefly introduce glabridin, which is derived from the plant glabridin. It is a member of the licorice flavonoid family. It has been found to have superior performance in tests including, anti-inflammatory, anti-tumor, anti-aging, and whitening.


Glabridin is widely regarded as a phytoestrogen with a variety of biological properties ranging from antioxidant, anti-inflammatory, neuroprotective, and anti-atherosclerotic effects to energy metabolism regulation, and also includes anti-tumorigenic, anti-renal, and antibacterial properties. It also has important value in skin antioxidant and blemish whitening, as well as preventing UV-induced inflammation and skin roughness.


Glabridin inhibits melanin production mainly through three directions: inhibition of reactive oxygen species production; inhibition of tyrosinase activity; and inhibition of inflammation.


Glabridin has a very good inhibitory effect on tyrosinase activity. Glabridin can form a hydrogen bond with the active center of tyrosinase and firmly stuck at the entrance of tyrosinase, so that the raw material of melanin synthesis cannot enter and the semi-finished product of melanin cannot exit, reducing melanin production.


The cause of darkening of the skin in normal health is from tyrosinase and reactive oxygen species. Tyrosinase produces melanin on a regular basis, which changes the skin or eyes from brown to black. 


And external stimuli (including common UV rays, inflammation, allergies, etc.) can cause it to be overproduced, thus darkening the person. The UV-induced generation of reactive oxygen species destroys the phospholipid membrane of skin tissue, and this histological change is manifested by the appearance of erythema and hyperpigmentation, so reactive oxygen species is a substance that can cause skin pigmentation, so inhibiting its production inhibits melanin production. 


Glabridin inhibits melanin synthesis by competitively inhibiting tyrosinase activity, taking away part of the tyrosinase from the catalytic ring of melanin synthesis and preventing the binding of substrates to tyrosinase, and also because glabridin itself has a good antioxidant effect. It has been proved that it is similar to superoxidedismutase (SOD) in scavenging oxygen free radicals and similar to vitamin E. 


It can inhibit both the activity of tyrosinase and dopa pigment interchange and dihydroxyindole carboxylic acid oxidase, which is a kind of fast, efficient and green cosmetic additive for whitening and spot removal. Some experimental data show that the whitening effect of glabridin is 232 times higher than that of ordinary vitamin C, 16 times higher than that of hydroquinone, and 1164 times higher than that of "arbutin".


OnenessPoint provides high quality light glycyrrhizin and stable supply, looking forward to cooperating with you!


If you have any questions, please contact us via email or telephone and we will get back to you as soon as possible.

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